The endocannabinoid system ("ECS") has been shown to regulate the immune system both in living organisms and in lab testing through its immunomodulatry mechanisms.
Cannabinoids suppress inflammatory signals and diminish disease symptoms through the following mechanisms:
Cannabinoids have shown in several experimental studies and autoimmune disorder models (including, but not limited to, colitis, hepatitis, multiple sclerosis, and rheumatoid arthritis) to protect the host from disease development.
Cannabinoids directly inhibit tumor growth in cancers that are triggered by chronic inflammation. CBD, in particular, suppresses inflammation and tumor angiogenesis (the migration, growth, and development of tumors through blood vessel development.)
Cannabidiol ("CBD") is effective in protecting the integrity and function of coronary artery cells.
CBD prevents psychotic-like symptoms induced by high doses of THC.
CBD has antipsychotic mechanisms in humans and animals by reversing psychosis instigator in the striatum and temporal cortex.
CBD has the pharmacological profile similar to atypical antipsychotic drugs.
CBD prevented human experimental psychosis and was effective in clinical trials in patients with schizophrenia.
62% of the study participants used CBD for 1) Pain, 2) Anxiety, 3) Depression, and 4) Sleep Disorders
36% of the study particpants said CBD treated their medical conditions "very well by itself"
Only 4.3% of the study participants said CBD treated their medical conditions "not very well"
Odds of using CBD as a medicine to treat conditions is 44% higher among non-regular users of cannabis than among regular users.
The use of CBD among individuals "for both specific health conditions and general health and well-being is widespread".
The most common way to learn about CBD is through the "internet, friends, or family members, rather than healthcare professionals."
A large percentage of respondents indicate that CBD treats their condition(s) effectively in the absense of conventional medicine and with nonserious adverse effects.
Most Reported Medical Conditions for CBD Use:
Reported Best Ways to Administer CBD
CBD is derived directly from the hemp plant, a cousin, but distinctly seperate, of the marijuana plant
The World Health Organization writes,
“In humans, CBD exhibits no effects indicative of any abuse or dependence potential… To date, there is no evidence of public health related problems associated with the use of pure CBD”
All 50 states have legalized CBD with varying degrees of restriction. Personal consumption is legal within the entire United States.
FDA gave the green lights for research trials in December 2015.
The federal government has legalized CBD from the hemp plant. The federal government's current position is that CBD from the marijuana plant is illegal, but this law has not been enforced in decades. They even have a patent on the subject!
So far, the strongest, irrefutable scientific evidence is its effectiveness for treating cruel childhood epilepsy syndromes, such as Dravet Syndrome and Lennox-Gastaut Syndrome (“LGS”). Most epilepsy syndromes in children do not respond to typical anti-seizure medications. CBD has played an important role in furthering research in this area. The range of relief goes from reduction in intensity of seizures to stoppage altogether.
Epidiolex, the first ever cannabis-derived medicine, has CBD as a main ingredient and was recently approved by the FDA.
CBD helps with anxiety, as the most desirable effect for a majority of patients is help with falling and staying asleep.
CBD beats the pharmaceutical industry with its success in inhibiting inflammatory and neuropathic pain, two of Western science’s most difficult types of chronic pain to treat.
